- Fr. Timothy Jock 1911–1916
- Rt. Rev. Exarch Cyril Aneid 1916–1921
- Rev. Peter Nahas 1921–1926
- Rt. Rev. Archimandrite Joseph Kandalaft 1926–1934
- Rev. Raphael Gedah, BSO 1934–1963
- Rev. John Nasser 1963–1967
- Rev. John Orlowski 1967–1968
- Rev. Elias Njaim 1968–1970
- Rev. Ronald Golini 1970–1977, 1978–1979
- Rev. Alexander Kelliher, S.A. 1977–1978
- Rev. Damon Geiger, O.Ss.T 1979–1982
- Rev. Frank Milienewicz 1982–1988
- Rev. Paul Frechette 1988–1990
- Rev. Cyril Crume 1990–1992
- Deacon Dimitry Kamolov, administrator 1992–1995
- V. Rev. Philaret Littlefield 1995–2017
- Mr. Benjamin Neumann, administrator 2017–2019
- Rt. Rev. Paul G. Frechette 2019–present
